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What is Pain?

Pain is a general term used to refer to uncomfortable sensations in the body. It is an unpleasant sensory and emotional experience. But at the same time, it is the body’s most important communication tool.
Pain is the body’s way to intimate the brain about an injury or illness. It is meant to make us uncomfortable so that if we are injured or sick, we know that we need to do something or stop doing something immediately.

How does Cannabis help with Pain?

CBD is a chemical compound naturally present in the Cannabis plant. It is said to have anti-inflammatory properties that provide relief from both acute and chronic pain.
To understand how CBD works for pain and pain-related symptoms, it is imperative to learn the functions of the Endocannabinoid System.

Potential Benefits of Cannabis for Pain

The breakdown of CBD, a compound in the Cannabis plant, helps it to be carried across the blood-brain barrier, affecting the central nervous system, where it can show a broad range of pain-relieving effects.
  • Reducing Pain Signals: CBD stimulates the reuptake of adenosine, boosting its levels in the brain and inhibiting pain sensations. CBD can also block pain signals from reaching the processing centres in the brain by binding to TPRV1—the receptor responsible for pain and inflammation.
  • Reducing Inflammation: CBD acts as an antioxidant and decreases oxidative stress and systematic inflammation in the body. Inflammation is the root cause of most pain. By decreasing inflammation in the body, CBD reduces the intensity of pain. CBD can also reduce neuropathic pain by countering hyperalgesia (an abnormally heightened pain response in the body).
  • Increasing Immune Response: Whenever our body experiences an injury, the body’s innate immune responds to it with an inflammatory response that activates the pain pathways. CBD can modulate this immune response by decreasing the levels of the pro-inflammatory cytokines thus decreasing pain.
  • Improving Mood & Sleep: Severe and chronic pain can cause psychological distress leading to depression, anxiety, irritability, and lack of peaceful sleep. CBD’s anxiolytic properties can reduce the overall stress in the body, leading to restful sleep.